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KMID : 0617320030120010143
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Journal of Pharmacetical Sceiences Ewha Womans University
2003 Volume.12 No. 1 p.143 ~ p.152
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Development of Ultrasonication-assisted Extraction Process for Manufacturing Extracts with High Contents of Pinosylvin from Pine Leaves
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조용진/Cho, Y. J.
이상국/안용현/피재호/Lee, S. K./Ahn, Y. H./Pyee, J. H.
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Abstract
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Pinosylvin, a stilbenoid phytoalexin, is a health ingredient to be extracted from pine leaves. In this study, ultrasonication-assisted extraction process for manufacturing extracts with high content of pinosylvin from pine leaves was investigated. As process and system variables, ultrasonic power, sonication time and solvent ratio were selected. According to the experimental results, the effective yield of pinosylvin increased with the increase of ultrasonic power and sonication time and the decrease of solvent ratio. When the ultrasonic power of 2400 W/L was added to the solution of pulverized pine leaves of 8 g per 1 L of a solvent for 10 minutes, yield of extracts and purity, effective yield and concentration ratio of pinosylvin were 0.3166 g/g, 0.7247 ㎎/g, 0.2294 ㎎/g and 23.0, respectively.
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